Epicydes served, together with his elder brother Hippocrates, with much distinction in the army of Hannibal, both in Spain and Italy. and when, after the battle of Cannae, Hieronymus of Syracuse sent to make overtures to Hannibal, that general selected the two brothers as his envoys to Syracuse. They soon gained over the wavering mind of the young king, and induced him to desert the Roman alliance. But the murder of Hieronymus shortly after, and the revolution that ensued at Syracuse, for a time deranged their plans. At first, they demanded merely a safe-conduct to return to Hannibal. But they soon found that they could do more good by their intrigues at Syracuse, where they even succeeded in procuring their election as generals in the place of Andranodorus and Themistus.